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Image Search Results
Journal: American Journal of Alzheimer's Disease and Other Dementias
Article Title: Sulforaphane Ameliorates Neurobehavioral Deficits and Protects the Brain From Amyloid β Deposits and Peroxidation in Mice With Alzheimer-Like Lesions
doi: 10.1177/1533317514542645
Figure Lengend Snippet: Analyses of oxidative stress levels in the cerebral cortex of mice. Compared with control, a significant increase in carbonyl group level (A) and obvious decreases in both GPX activity and relative GPX mRNA expression (C and D) were found in brain of AD mice but not in AD+SFN mice. However, there were not statistically different in sulfhydryl group level (B), relative superoxide dismutase (SOD) activity, and mRNA expression (E and F) in mice brain among groups (n = 10; mean ± standard error of the mean [SEM]; one-way analysis of variance [ANOVA] with post hoc least significant difference [LSD] tests; *P < .05 vs the control group, # P < .05 vs the AD group). AD indicates Alzheimer’s disease; GPX, glutathione peroxidase; mRNA, messenger RNA; SFN, sulforaphane.
Article Snippet: According to the manufacturer’s instructions, total messenger RNA (mRNA) from the cerebral cortex of mice was isolated using
Techniques: Activity Assay, Expressing